You will probably have dozens of rejections from potential employers before you land a position. This constant barrage of negative responses can have a damaging effect on even the most optimistic person.
“When you don’t get a response from a resume or interview, it’s okay to take a few moments to mourn the loss of an opportunity,” said Judy Reeves, Executive Career Consultant at Stewart, Cooper and Coon, Inc. “However, you must then boost yourself back up by believing that there is something better waiting for you.”
Keep in mind that not matching a certain company's criteria doesn't mean you're not worthy. You're still a talented professional with the ability to contribute a wealth of knowledge and ideas.